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NMP (N-Methylpyrrolidone)

NMP (N-Methylpyrrolidone) Introduction:

N-Methylpyrrolidone, also known as NMP or 1-methyl-2-pyrrolidone). NMP (N-Methylpyrrolidone) produced by Welinks is an aprotic, highly polar organic solvent used in a variety of industries and applications.

Name NMP (N-Methylpyrrolidone)(N-Methyl-2-pyrrolidone)
Molecular Formula C5H9NO
CAS No. 872-50-4
Package 200KG Steel drums 1000KG Composite IBC Bulk
Molecular Weight 99.15
Mass Percentage (%) ≥99.90%

N-Methylpyrrolidone Applications Include:

Peptide synthesis in the pharmaceutical industry;
Membrane manufacture, for example, polyvinylidene fluoride (PVDF), polyvinylpyrrolidone (PVP)and polyether sulfone (PES);
Lithium ion battery production;
Coatings, inks and resins;
Crop protection formulations and active ingredient synthesis;
Oil extraction processes;
paint and coating removal.


N-methylpyrrolidone Harms:

Overview of hazards: flammable liquid and vapor. Will cause irritation to skin, eyes and respiratory tract. Harmful if swallowed, inhaled or absorbed through the skin.
Skin: N-methyl-2-pyrrolidone can cause itching, redness, peeling and hives. It can be quickly absorbed through the skin and can transport other dissolved toxins into the body.
Eyes: Irritating to eyes and can cause corneal burns.
Inhalation: May cause respiratory irritation, headache, nausea, dizziness and drowsiness.
Ingestion: can cause dizziness, drowsiness, nausea, vomiting, cramps and chills.
Delayed effect: can cause liver and kidney damage.


Skin: Rinse skin with water for at least 15 minutes while removing contaminated clothing and safety shoes. Seek medical attention if irritation or any other symptoms occur.
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes. Seek medical attention.
Inhalation: Move the victim to fresh air. If breathing stops, give artificial respiration. If breathing is difficult, give oxygen therapy by qualified personnel. Seek medical attention immediately.
Ingestion: If you are still conscious, rinse your mouth with water. The patient can dilute the stomach dissolve by drinking water or milk. Unless you are guided by a medical professional, you should not induce vomiting by yourself. Seek medical attention immediately.
Advice to the doctor: No special advice. Treat the symptoms.

Fire-fighting Measures
Flammable Characteristics Flash Point 187℉(88℃)
Flash Point Determination Method Closed Cup Method
Auto-ignition Temperature 346°C
Flammable Upper Limit (Volume Percentage in Air%) 9.5%
Lower Flammable Limit (Volume percentage in Air%) 1.3%
Flame Propagation Rate (Solid) not applicable
Fire Fighting Methods Extinguish fire with carbon dioxide, dry chemicals or foam.
Rare Fire and Explosion Hazards Heat will increase the internal pressure of the container and cause it to rupture. When heated to above the flash point, it will form an explosive mixture with gas.
Special Fire Warning/Cautions Wear full protective clothing and self-control respirator with full face mask.

Accidental Leakage Measures:

Splashes or Other Spills:
Always wear recommended personal protective equipment, remove ignition sources, and isolate spilled areas.
If possible, use tools to hold and recover spilled liquid. Absorb a small amount of spilled liquid with an inert material and place it in an approved chemical waste container. For large spills, the application of inert materials will spill the area. Enclose the embankment and transfer it into the same container as above, not allowing it to flow into the sewer or drainage ditch.
Splashes and leaks may need to be reported by the local government.

Operation and Storage:

Routine Operation:

Always wear recommended personal protective equipment and keep away from heat and open flames.
Adequate ventilation should be maintained when using this product. Avoid contact with skin, eyes and clothing. Do not eat, drink or smoke in the work area.
Wash thoroughly after handling this product.

Storage Recommendations:

Keep this product in a cool, dry, well-ventilated place, away from heat, ignition sources and incompatible substances.
This product should keep the container upright and tightly closed. Physical damage to the container should be avoided. Do not reuse the container.
Empty containers may contain residual product and/or vapors. Unwashed empty containers should be labelled as a warning.

Exposure Control/Personal Protection:

Engineering control: Ensure that adequate mechanical ventilation is provided. Local ventilation should be used at the place where this product is loaded, unloaded or transferred.

Personal protective equipment:
Skin protection: impermeable protective clothing should be worn, including work shoes, gloves, laboratory clothes, aprons or work clothes to avoid contact with liquids.
Eye protection: Wear non-porous protective glasses during routine operation. Determine whether to use goggles or full face masks according to the number of products and the environment in which they are used.
Respiratory protection: No protective measures are required in well-ventilated areas. If there is a potential for inhalation of vapour or mist, a NIOSH approved respirator should be used.
caveat! Air purifying respirators cannot protect workers in an oxygen-deficient environment. The respirator should be selected according to the degree of contamination of the work area and the environment in which it is used. The operating environment must not exceed the working limit of the respirator.

Other suggestions: Eyewash devices and safety showers should be provided near the work area.

Physical and Chemical Properties
Appearance Colorless and Transparent
Physical Form Liquid
Odor Amine-like Odor
Specific Gravity (1.0 for water) 1.03
Water Solubility (% by mass) 100%
PH Not applicable
Boiling Point 202℃ (396℉)
Melting Point -11℉(-24℃)
Vapor Pressure <1 mmHg at 68℉(20oC)
Vapor density (air is 1.0) 3.4
Evaporation Rate >1 (control: the evaporation rate of butyl acetate is 1)
Percentage of Volatile Matter (%) ~100

Stability and Reactivity:

Normally: stable.
Conditions to avoid: Stable under normal use and storage conditions. Avoid heat, open flames, ignition sources and incompatible materials.
Incompatible materials: oxidizing agents and strong acids.
Hazardous decomposition products: high temperature decomposition will produce carbon monoxide, carbon dioxide and nitrogen oxides.
Dangerous polymerization: will not happen.

Packaging and Shipping Information:

NMP (N-Methylpyrrolidone) is highly hygroscopic and easily absorbs moisture in the air. Pay attention to sealing and moisture-proof. It is chemically inactive and non-corrosive to other metals such as carbon steel and aluminum, except for copper. Packed in galvanized iron drum, 50kg or 200kg per drum. Store and transport in accordance with general chemical regulations.

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