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How to Prepare N-methyl 2-pyrrolidone


How to prepare N-methyl 2-pyrrolidone

N-Methyl 2-pyrrolidone is an important chemical raw material that can be prepared by a variety of methods. Here are a few common preparation methods:

Reaction of pyrrole and methylamine: Mix pyrrole and methylamine, heat to above 80°C, react for 5-6 hours, and then go through cooling, separation, drying and other steps to obtain the NMP product. This method is the simplest and most commonly used method to prepare NMP.
Reaction of pyrrole and acetic anhydride: React pyrrole and acetic anhydride in the presence of a catalyst to generate N-methylpyrrolidone. This method can obtain high-purity NMP products.
Reaction of propylene oxide and ammonia: React propylene oxide and ammonia under certain conditions to generate N-methylpyrrolidone. The NMP product obtained by this method has higher purity, but requires the use of special catalysts and equipment.
Polymerization of N-methylpyrrolidone: Polymerize N-methylpyrrolidone monomer to obtain polymer materials. The cost of this method is relatively high, but the resulting polymer material has high mechanical strength and corrosion resistance.
It should be noted that different preparation methods may produce NMP products of different qualities, so the choice of preparation method needs to be based on actual conditions. In addition, you need to pay attention to its toxicity and irritation when using NMP, and take appropriate safety measures.

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